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Article

Predominant DICER1 Pathogenic Variants in Pediatric Follicular Thyroid Carcinomas.

Thyroid : official journal of the American Thyroid Association - 1 Aug 2020

Lee Young Ah, Im Sun-Wha, Jung Kyeong Cheon, Chung Eun-Jae, Shin Choong Ho, Kim Jong-Il, Park Young Joo

Abstract excerpt

Background: Pediatric thyroid cancer has characteristics that are distinct from adulthood thyroid cancer. Due to its very low prevalence, little is known about the genetic characteristics of pediatric follicular thyroid cancer (FTC). Methods: We investigated genetic alterations in tumor tissues from 15 patients aged <20 years (median: 14.3 years; range: 2.4 - 19.0 years) using multifaceted approaches. Whole-exome...

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PMID: 32228164
DOI: 10.1089/thy.2019.0233

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