Article
[Effect of low concentration paraquat on activation of mouse microglia M1/M2 phenotypes].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases - 20 Dec 2019
Li Y Y, Wu K X, Tian T, Wang Y F, Yan W G, Huang M
Abstract excerpt
Objective: To observe the effect of low concentration paraquat (PQ) on activation and phenotypic M1/M2 polarization of mouse microglia cells (BV2) . Methods: BV2 cells were used as model, and cultured in vitro were exposed to paraquat at designed concentrations of 0, 0.015, 0.03, 0.06, 0.12, 0.24, 0.48 μmol/L and 0.05 μmol/L 1-methyl-4-phenylpyridinium (MPP(+)) for 24 h, and cell viability was determined by CCK8...
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