Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential role for survivin in early brain development.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Jul 2005

Jiang Yuying, de Bruin Alain, Caldas Hugo, Fangusaro Jason, Hayes John, Conway Edward M, Robinson Michael L, Altura Rachel A

Abstract excerpt

Apoptosis is an essential process during normal neuronal development. Approximately one-half of the neurons produced during neurogenesis die before completion of CNS maturation. To characterize the role of the inhibitor of apoptosis gene, survivin, during neurogenesis, we used the Cre-loxP-system to generate mice lacking survivin in neuronal precursor cells. Conditional deletion of survivin starting at embryonic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inhibitor of Apoptosis Proteins
Share to Integrases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intermediate Filament Proteins

Share to Mice, Mutant Strains

Share to Microtubule-Associated Proteins

Share to Nestin

Share to Retina

Share to Survivin

Source

Open in PubMed Open full text

Identifiers

PMID: 16049172
DOI: 10.1523/JNEUROSCI.1446-05.2005
PMCID: PMC6724828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential role for survivin in early brain development.PMID 16049172Read ↗

Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells.Semantic proximity Read ↗

Essential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis.Semantic proximity Read ↗

Survivin: A Bifunctional Inhibitor of Apoptosis ProteinSemantic proximity Read ↗

Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic StrategiesSemantic proximity Read ↗

Survivin: Role in Normal Cells and in Pathological ConditionsSemantic proximity Read ↗

An IAP in Action: The Multiple Roles of Survivin in Differentiation, Immunity and MalignancySemantic proximity Read ↗

Survivin study: What is the next wave?Semantic proximity Read ↗

Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage.Semantic proximity Read ↗

Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure.Semantic proximity Read ↗

Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions.Semantic proximity Read ↗

p63 antagonizes p53 to promote the survival of embryonic neural precursor cells.Semantic proximity Read ↗

p53 deletion rescues lethal microcephaly in a mouse model with neural stem cell abscission defectsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.