Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2.

PloS one - 1 Jan 2020

Faramarz Atiq, Balk Jesper A, van Schie Janne J M, Oostra Anneke B, Ghandour Cherien A, Rooimans Martin A, Wolthuis Rob M F, de Lange Job

Abstract excerpt

In a process linked to DNA replication, duplicated chromosomes are entrapped in large, circular cohesin complexes and functional sister chromatid cohesion (SCC) is established by acetylation of the SMC3 cohesin subunit. Roberts Syndrome (RBS) and Warsaw Breakage Syndrome (WABS) are rare human developmental syndromes that are characterized by defective SCC. RBS is caused by mutations in the SMC3 acetyltransferase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyltransferases
Share to Chromatids

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Breakage

Share to Cohesins

Share to Craniofacial Abnormalities

Share to DEAD-box RNA Helicases

Share to Ectromelia

Share to Hypertelorism

Source

Open in PubMed Open full text

Identifiers

PMID: 31935221
DOI: 10.1371/journal.pone.0220348
PMCID: PMC6959578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2.PMID 31935221Read ↗

Non-Redundant Roles in Sister Chromatid Cohesion of the DNA Helicase DDX11 and the SMC3 Acetyl Transferases ESCO1/2Semantic proximity Read ↗

The molecular mechanism underlying Roberts syndrome involves loss of ESCO2 acetyltransferase activity.Semantic proximity Read ↗

Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome.Semantic proximity Read ↗

Region-specific generation and retention of acetylated cohesin shape the genome-wide pattern of sister chromatid cohesionSemantic proximity Read ↗

The acetyltransferase Eco1 elicits cohesin dimerization during S phaseSemantic proximity Read ↗

How many roads lead to cohesinopathies?Semantic proximity Read ↗

Brca2, Pds5 and Wapl differentially control cohesin chromosome association and functionSemantic proximity Read ↗

Cell biology: cohesin ring exit gate revealed.Semantic proximity Read ↗

Role of the DDX11 DNA Helicase in Warsaw Breakage Syndrome Etiology.Semantic proximity Read ↗

CRISPR screens in sister chromatid cohesion defective cells reveal PAXIP1-PAGR1 as regulator of chromatin association of cohesinSemantic proximity Read ↗

Cohesin and human disease.Semantic proximity Read ↗

Cohesin composition and dosage independently affect early development in zebrafishSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.