Article
Computational analyses prioritize and reveal the deleterious nsSNPs in human angiotensinogen gene.
Computational biology and chemistry - 1 Feb 2020
Goswami Achintya Mohan
Abstract excerpt
Angiotensinogen (AGT) is a key component of renin-angiotensin-aldosterone system (RAAS), which plays central role in blood pressure homeostasis. Association of AGT polymorphisms have been investigated in different ethnic populations in variety of cardiovascular and non-cardiovascular conditions. In this study, 354 non-synonymous SNPs (nsSNPs) of AGT were evaluated to predict damaging and structurally important...
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