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Article

Association of Hypercholesterolemia with Alzheimer's Disease Pathology and Cerebral Amyloid Angiopathy.

Journal of Alzheimer's disease : JAD - 1 Jan 2020

Xu Chenjia, Apostolova Liana G, Oblak Adrian L, Gao Sujuan

Abstract excerpt

BACKGROUND: Animal studies have shown that diet-induced hypercholesterolemia (HC) increases amyloid-β (Aβ) accumulation and accelerates Alzheimer's disease (AD) pathology. However, the association of HC with AD in human studies has not been consistently established. OBJECTIVE: We aimed to investigate the relationship between HC and risk of AD neuropathology in a large national sample with autopsies. METHODS: This...

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Identifiers

PMID: 31929164
DOI: 10.3233/JAD-191023
PMCID: PMC7489304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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