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Article

Cerebral amyloid angiopathy and Alzheimer's and related pathologies across APOE genotypes.

Brain : a journal of neurology - 3 Aug 2026

Mehta Rupal I, Wang Tianhao, Leurgans Sue E, Bennett David A, Schneider Julie A

Abstract excerpt

Cerebral amyloid angiopathy (CAA) is associated with age, apolipoprotein E (APOE) genotype, and a pathologic diagnosis of Alzheimer's disease (AD). Yet, the complete spectrum of CAA presence and severity across age, APOE genotype, AD and AD-related disorders (ADRD) is incompletely reported. Additionally, recent experiments suggest associations between CAA and diffuse plaques. Here, we studied CAA in older adults...

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Source

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Identifiers

PMID: 41566952
DOI: 10.1093/brain/awag025
PMCID: PMC13431795

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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