Haptoglobin genotype and outcome after spontaneous intracerebral haemorrhage.

doi:10.1136/jnnp-2019-321774

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Haptoglobin genotype and outcome after spontaneous intracerebral haemorrhage.

Journal of neurology, neurosurgery, and psychiatry - 1 Mar 2020

Hostettler Isabel Charlotte, Morton Matthew J, Ambler Gareth, Kazmi Nabila, Gaunt Tom, Wilson Duncan, Shakeshaft Clare, Jäger H R, Cohen Hannah, Yousry Tarek A, Al-Shahi Salman Rustam, Lip Gregory, Brown Martin M, Muir Keith, Houlden Henry, Bulters Diederik O, Galea Ian, Werring David J

Abstract excerpt

OBJECTIVE: Haptoglobin is a haemoglobin-scavenging protein that binds and neutralises free haemoglobin and modulates inflammation and endothelial progenitor cell function. A HP gene copy number variation (CNV) generates HP1 and HP2 alleles, while the single-nucleotide polymorphism rs2000999 influences their levels. The HP1 allele is hypothesised to improve outcome after spontaneous (non-traumatic) intracerebral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cerebral Hemorrhage

Share to Cohort Studies

Share to DNA Copy Number Variations

Share to Haptoglobins

Share to Polymorphism, Single Nucleotide

Share to Recovery of Function

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 31924654
DOI: 10.1136/jnnp-2019-321774
PMCID: PMC7612606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Haptoglobin genotype and outcome after spontaneous intracerebral haemorrhage.PMID 31924654Read ↗

Haptoglobin genotype and outcome after aneurysmal subarachnoid haemorrhage.Semantic proximity Read ↗

Haptoglobin Genotype and Outcome after Subarachnoid Haemorrhage: New Insights from a Meta-Analysis.Semantic proximity Read ↗

Presence of haptoglobin-2 allele is associated with worse functional outcomes after spontaneous intracerebral hemorrhage.Semantic proximity Read ↗

Genetic Polymorphisms Associated with Spontaneous Intracerebral HemorrhageSemantic proximity Read ↗

Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage.Semantic proximity Read ↗

Haptoglobin genotype and functional outcome after aneurysmal subarachnoid hemorrhage.Semantic proximity Read ↗

The Ethnic/Racial Variations of Intracerebral Hemorrhage Genetics (ERICH-GENE) Study ProtocolSemantic proximity Read ↗

Genetics of cerebral hemorrhage and microbleeds.Semantic proximity Read ↗

Genetic risk of Spontaneous intracerebral hemorrhage: Systematic review and future directions.Semantic proximity Read ↗

Haptoglobin phenotype predicts the development of focal and global cerebral vasospasm and may influence outcomes after aneurysmal subarachnoid hemorrhage.Semantic proximity Read ↗

Aquaporin-4 gene variant independently associated with oedema after intracerebral haemorrhage.Semantic proximity Read ↗

Complement Factor H Y402H polymorphism is associated with an increased risk of mortality after intracerebral hemorrhage.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.