Haptoglobin genotype and functional outcome after aneurysmal subarachnoid hemorrhage.

doi:10.3171/2013.10.JNS13219

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Article

Haptoglobin genotype and functional outcome after aneurysmal subarachnoid hemorrhage.

Journal of neurosurgery - 1 Feb 2014

Kantor Ellen, Bayır Hülya, Ren Dianxu, Provencio J Javier, Watkins Laura, Crago Elizabeth, Horowitz Michael B, Ferrell Robert E, Conley Yvette P, Alexander Sheila A

Abstract excerpt

OBJECT: Haptoglobin allele heterogeneity has been implicated in differential reactive oxidant inhibition and inflammation. Haptoglobin α2-α2 has a lower affinity for binding hemoglobin, and when bound to hemoglobin, is cleared less easily by the body. The authors hypothesized that haptoglobin α2-α2 genotype should be less protective for downstream injury after aneurysmal subarachnoid hemorrhage (aSAH) and should...

Topics

Adolescent
Adult
Aged
DNA
Data Interpretation, Statistical
Female
Genotype
Glasgow Coma Scale
Haptoglobins
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Neurosurgical Procedures

Prognosis

Real-Time Polymerase Chain Reaction

Socioeconomic Factors

Subarachnoid Hemorrhage

Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 24286153
DOI: 10.3171/2013.10.JNS13219
PMCID: PMC4544750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24286153-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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