Article
Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage.
Stroke - 1 Feb 2013
Falcone Guido J, Biffi Alessandro, Devan William J, Brouwers H Bart, Anderson Christopher D, Valant Valerie, Ayres Alison M, Schwab Kristin, Rost Natalia S, Goldstein Joshua N, Viswanathan Anand, Greenberg Steven M, Selim Magdy, Meschia James F, Brown Devin L, Worrall Bradford B, Silliman Scott L, Tirschwell David L, Rosand Jonathan
Abstract excerpt
BACKGROUND AND PURPOSE: Intracerebral hemorrhage (ICH) is the acute manifestation of a progressive disease of the cerebral small vessels. The severity of this disease seems to influence not only risk of ICH but also the size of the hematoma. As the burden of high blood pressure-related alleles is associated with both hypertension-related end-organ damage and risk of ICH, we sought to determine whether this burden...
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