Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The <i>ISG56/IFIT1</i> Gene Family

15 Oct 2010

Abstract excerpt

The ISG56/IFIT1 family of genes is clustered on human chromosome 10 and is comprised of 4 members, ISG56/IFIT1, ISG54/IFIT2, ISG60/IFIT3, and ISG58/IFIT5, whose homologs are evolutionarily conserved from mammals to amphibians. While these genes are normally silent in most cell types, their transcription is strongly induced by interferons, virus infection, and molecular patterns such as double-stranded RNA or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune Response and Inflammation
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20950130
DOI: 10.1089/jir.2010.0101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The <i>ISG56/IFIT1</i> Gene FamilyPMID 20950130Read ↗

IFI60/ISG60/IFIT4, a New Member of the Human IFI54/IFIT2 Family of Interferon-Stimulated GenesSemantic proximity Read ↗

Interferon induced IFIT family genes in host antiviral defense.Semantic proximity Read ↗

IFITM protein regulation and functions: Far beyond the fight against virusesSemantic proximity Read ↗

Interferon-Induced Ifit Proteins: Their Role in Viral PathogenesisSemantic proximity Read ↗

The emerging roles of IFIT3 in antiviral innate immunity and cellular biologySemantic proximity Read ↗

Emerging Functions of Human IFIT Proteins in CancerSemantic proximity Read ↗

IFITM Genes, Variants, and Their Roles in the Control and Pathogenesis of Viral InfectionsSemantic proximity Read ↗

Interferon-stimulated gene IFI27 as a multifaceted candidate target in precision medicineSemantic proximity Read ↗

IFITM proteins: Understanding their diverse roles in viral infection, cancer, and immunitySemantic proximity Read ↗

IFIT5 potentiates anti-viral response through enhancing innate immune signaling pathwaysSemantic proximity Read ↗

Roles of Interferon Induced Protein with Tetratricopeptide Repeats (IFIT) Family in CancerSemantic proximity Read ↗

IFITM-Family Proteins: The Cell's First Line of Antiviral DefenseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.