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Article

FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer

9 Jan 2020

Abstract excerpt

BACKGROUND: Low expression of FOXE1, a member of Forkhead box (FOX) transcription factor family that plays vital roles in cancers, contributes to poor prognosis of colorectal cancer (CRC) patients. However, the underlying mechanism remains unclear. MATERIALS AND METHODS: The effects of FOXE1 on the growth of colon cancer cells and the expression of glycolytic enzymes were investigated in vitro and in vivo....

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PMID: 31918722
DOI: 10.1186/s12964-019-0502-8

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