Article

Transcription factor ONECUT3 regulates HDAC6/HIF-1α activity to promote the Warburg effect and tumor growth in colorectal cancer

2024-05-23

Abstract excerpt

<title>Abstract</title> <p>The Warburg effect, also known as aerobic glycolysis, plays a crucial role in the onset and progression of colorectal cancer, although its mechanism remains unclear. Bioinformatics analysis of public databases and verification of clinical specimens revealed that the transcription factor ONECUT3 is a key regulator related to the Warburg effect in colorectal cancer. Functionally, genetic...

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Literature Corpus work: a9d75c45-7024-5def-bdc4-3424aad6c943
DOI: 10.21203/rs.3.rs-4296431/v1

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