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IFN-γ orchestrates tumor elimination, tumor dormancy, tumor escape, and progression

22 Feb 2018

Abstract excerpt

Tumor immunoediting consisting of three phases of elimination, equilibrium or dormancy, and escape has been supported by preclinical and clinical data. A comprehensive understanding of the molecular mechanisms by which antitumor immune responses regulate these three phases are important for developing highly tailored immunotherapeutics that can control cancer. To this end, IFN-γ produced by Th1 cells, cytotoxic T...

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PMID: 29469956
DOI: 10.1002/jlb.5mir0917-351r

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