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Article

Phenotypic and microRNA characterization of the neglected CD24+ cell population in MCF-7 breast cancer 3-dimensional spheroid culture.

Journal of the Chinese Medical Association : JCMA - 1 Jan 2020

Boo Lily, Yeap Swee Keong, Ali Norlaily Mohd, Ho Wan Yong, Ky Huynh, Satharasinghe Dilan Amila, Liew Woan Charn, Tan Sheau Wei, Wang Mong-Lien, Cheong Soon Keng, Ong Han Kiat

Abstract excerpt

BACKGROUND: In vitro 3-dimensional (3D) spheroid culture has been widely used as model to enrich CD44CD24 cancer stem cells (CSC) with high aldehyde dehydrogenase 1 (ALDH1) activity. Although CD24 subpopulation was known to be present in 3D spheroids and may influence cancer drug therapies, its characteristics and CSC properties were not well defined. METHODS: In this study, CD24 population from the Michigan...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31904742
DOI: 10.1097/JCMA.0000000000000226
PMCID: PMC13048175

Genes

CD24
CD44

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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