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Article

CD44+/CD24- phenotype contributes to malignant relapse following surgical resection and chemotherapy in patients with invasive ductal carcinoma.

Journal of experimental & clinical cancer research : CR - 4 Jul 2012

Lin Yan, Zhong Ying, Guan Heng, Zhang Xiaohui, Sun Qiang

Abstract excerpt

BACKGROUND: Invasive ductal carcinoma is the most common type of breast malignancy, with varying molecular features and resistance to treatment. Although CD44+/CD24- cells are believed to act as breast cancer stem cells and to be linked to poor prognosis in some patients, the association between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22762532
DOI: 10.1186/1756-9966-31-59
PMCID: PMC3432011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22762532-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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CD44+/CD24- phenotype contributes to malignant relapse following surgical resection and chemotherapy in patients with invasive ductal carcinoma.PMID 22762532Read ↗

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CD44(+)/CD24(-) cells are transit progenitors and do not determine the molecular subtypes and clinical parameters in breast carcinomas.Semantic proximity Read ↗

The CD44+/CD24- phenotype is enriched in basal-like breast tumors.Semantic proximity Read ↗

Features of CD44+/CD24-low phenotypic cell distribution in relation to predictive markers and molecular subtypes of invasive ductal carcinoma of the breast.Semantic proximity Read ↗

CD44+/CD24‑ phenotype predicts a poor prognosis in triple‑negative breast cancerSemantic proximity Read ↗

Cancer stem cell markers ALDH1 and CD44+/CD24- phenotype and their prognosis impact in invasive ductal carcinomaSemantic proximity Read ↗

Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics.Semantic proximity Read ↗

Enriched CD44(+)/CD24(-) population drives the aggressive phenotypes presented in triple-negative breast cancer (TNBC).Semantic proximity Read ↗

Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype.Semantic proximity Read ↗

The CD44+/CD24- phenotype relates to 'triple-negative' state and unfavorable prognosis in breast cancer patients.Semantic proximity Read ↗

Prognosis assessment of CD44+/CD24- in Breast Cancer Patients: a systematic review and meta-analysisSemantic proximity Read ↗

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