Article
The CD44+/CD24- phenotype is enriched in basal-like breast tumors.
Breast cancer research : BCR - 1 Jan 2008
Honeth Gabriella, Bendahl Pär-Ola, Ringnér Markus, Saal Lao H, Gruvberger-Saal Sofia K, Lövgren Kristina, Grabau Dorthe, Fernö Mårten, Borg Ake, Hegardt Cecilia
Abstract excerpt
INTRODUCTION: Human breast tumors are heterogeneous and consist of phenotypically diverse cells. Breast cancer cells with a CD44+/CD24- phenotype have been suggested to have tumor-initiating properties with stem cell-like and invasive features, although it is unclear whether their presence within a tumor has clinical implications. There is also a large heterogeneity between tumors, illustrated by reproducible...
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