Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enriched CD44(+)/CD24(-) population drives the aggressive phenotypes presented in triple-negative breast cancer (TNBC).

Cancer letters - 28 Oct 2014

Ma Fei, Li Huihui, Wang Haijuan, Shi Xiuqing, Fan Ying, Ding Xiaoyan, Lin Chen, Zhan Qimin, Qian Haili, Xu Binghe

Abstract excerpt

The mechanism underlying the aggressive behaviors of triple negative breast cancer (TNBC) is not well characterized yet. The association between cancer stem cell (CSC) population and the aggressive behaviors of TNBC has not been established. We found the CD44(+)/CD24(-) cell population was enriched in TNBC tissues and cell lines, with a higher capacity of proliferation, migration, invasion and tumorigenicity as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Ductal, Breast
Share to CD24 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyaluronan Receptors

Share to Lymphatic Metastasis

Share to Mice, Inbred NOD

Share to Mice, SCID

Share to Neoplasm Transplantation

Share to Triple Negative Breast Neoplasms

Source

Identifiers

PMID: 25130168
DOI: 10.1016/j.canlet.2014.06.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enriched CD44(+)/CD24(-) population drives the aggressive phenotypes presented in triple-negative breast cancer (TNBC).PMID 25130168Read ↗

CD44+/CD24‑ phenotype predicts a poor prognosis in triple‑negative breast cancerSemantic proximity Read ↗

Transcriptional profiles of different states of cancer stem cells in triple-negative breast cancerSemantic proximity Read ↗

The CD44+/CD24- phenotype relates to 'triple-negative' state and unfavorable prognosis in breast cancer patients.Semantic proximity Read ↗

The distribution of CD44+/CD24- cancer stem cells in breast cancer and its relationship with prognostic factors.Semantic proximity Read ↗

Cancer stem cells are prevalent in the basal-like 2 and mesenchymal triple-negative breast cancer subtypes in vitroSemantic proximity Read ↗

Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics.Semantic proximity Read ↗

Functional heterogeneity within the CD44 high human breast cancer stem cell-like compartment reveals a gene signature predictive of distant metastasis.Semantic proximity Read ↗

Evaluation of Breast Cancer Stem Cells and Intratumor Stemness Heterogeneity in Triple-negative Breast Cancer as Prognostic FactorsSemantic proximity Read ↗

Novel molecular regulators of breast cancer stem cell plasticity and heterogeneitySemantic proximity Read ↗

CD44(+)/CD24(-) cells are transit progenitors and do not determine the molecular subtypes and clinical parameters in breast carcinomas.Semantic proximity Read ↗

Therapeutic vulnerabilities in triple negative breast cancer: Stem-like traits explored within molecular classification.Semantic proximity Read ↗

Circulating tumor cells with a putative stem cell phenotype in peripheral blood of patients with breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.