Article
Isolation and characterization of breast cancer stem cell-like phenotype by Oct4 promoter-mediated activity.
Journal of cellular physiology - 1 Nov 2020
Ghanei Zahra, Jamshidizad Abbas, Joupari Morteza Daliri, Shamsara Mehdi
Abstract excerpt
Cancer stem cells (CSCs) are a small subset of cancer cells responsible for self-renewal activity, drug resistance, and tumor recurrence. CSCs have been derived from diverse tumors and cell lines. The expression of stemness markers has been identified in CSCs. Oct4 is a well-established transcription factor expressed in stem cells and CSCs. In this study, we isolated and characterized breast CSC-like cells from...
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