Article
Phenotype molding of T cells in colorectal cancer by single-cell analysis.
International journal of cancer - 15 Apr 2020
Di Jiabo, Liu Maoxing, Fan Yingcong, Gao Pin, Wang Zaozao, Jiang Beihai, Su Xiangqian
Abstract excerpt
The majority of patients with microsatellite stable (MSS) colorectal cancer (CRC) do not benefit from the immunotherapies directed at rescuing T-cell functions. Therefore, complete understanding of T-cell phenotypes and functional status in the CRC microenvironment is desirable. Here, we applied single-cell mass cytometry to mold the T-cell phenotype in 18 patients with MSS CRC for better understanding of CRC as...
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