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Article

The functional and phenotypic diversity of single T-cell infiltrates in human colorectal cancer as correlated with clinical outcome

2020-09-28

Abstract excerpt

Although degree of T-cell infiltration in CRC was shown to correlate with a positive prognosis, the contribution of phenotypically and functionally distinct T cell subtypes within tumors remains unclear. We analyzed 37,931 single T cells with respect to transcriptome, TCR sequence and 23 cell surface proteins, from tumors and adjacent normal colon of 16 patients. Our comprehensive analysis revealed two phenotypica...

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Literature Corpus work
858bbe35-e844-5a2b-a4e0-46aecbc0a64c
DOI
10.1101/2020.09.27.313445
Open publication

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The functional and phenotypic diversity of single T-cell infiltrates in human colorectal cancer as correlated with clinical outcomeDOI 10.1101/2020.09.27.313445
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