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Article

Functional cell phenotype induction with TGF-β1 and collagen-polyurethane scaffold for annulus fibrosus rupture repair.

European cells & materials - 3 Jan 2020

Du J, Long R G, Nakai T, Sakai D, Benneker L M, Zhou G, Li B, Eglin D, Iatridis J C, Alini M, Grad S, Li Z

Abstract excerpt

Appropriate cell sources, bioactive factors and biomaterials for generation of functional and integrated annulus fibrosus (AF) tissue analogues are still an unmet need. In the present study, the AF cell markers, collagen type I, cluster of differentiation 146 (CD146), mohawk (MKX) and smooth muscle protein 22α (SM22α) were found to be suitable indicators of functional AF cell induction. In vitro 2D culture of...

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Identifiers

PMID: 31899537
DOI: 10.22203/eCM.v039a01
PMCID: PMC7027376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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