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Article

Mechanoregulation of valvular interstitial cell phenotype in the third dimension.

Biomaterials - 1 Jan 2014

Kural Mehmet H, Billiar Kristen L

Abstract excerpt

A quantitative understanding of the complex interactions between cells, soluble factors, and the biological and mechanical properties of biomaterials is required to guide cell remodeling toward regeneration of healthy tissue rather than fibrocontractive tissue. In the present study, we characterized the combined effects of boundary stiffness and transforming growth factor-β1 (TGF-β1) on cell-generated forces and...

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Source

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Identifiers

PMID: 24210873
DOI: 10.1016/j.biomaterials.2013.10.047
PMCID: PMC3876484

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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