Article

Developmental Morphogens Direct Human Induced Pluripotent Stem Cells Towards an Annulus Fibrosus-Like Cell Phenotype

2022-05-06

Abstract excerpt

Therapeutic interventions for intervertebral disc herniation remain scarce due to the inability of endogenous annulus fibrosus (AF) cells to respond to injury and drive tissue regeneration. Unlike other orthopaedic tissues, such as cartilage, delivery of exogenous cells to the site of annular injury remains underdeveloped, largely due to a lack of an ideal cell source and the invasive nature of cell isolation. Hum...

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Literature Corpus work: b526eac9-9e17-59f8-9a21-b7aa4a6d4e6a
DOI: 10.1101/2022.05.06.490483

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