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Article

Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia.

PloS one - 1 Jan 2020

Poddighe Dimitri, Turganbekova Aida, Baymukasheva Dana, Saduakas Zhazira, Zhanzakova Zhuldyz, Abdrakhmanova Saniya

Abstract excerpt

BACKGROUND: Celiac disease (CD) is a systemic immune-mediated disorder developing in HLA genetically predisposed individuals carrying HLA-DQ2 and/or HLA-DQ8 molecules. Recent evidences supported a predominant importance of HLA-DQB1 locus and, in particular, HLA-DQB1*02 alleles. This diagnosis is poorly considered in Kazakhstan, because of the assumption that CD is not prevalent in this population. OBJECTIVE: To...

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Identifiers

PMID: 31895924
DOI: 10.1371/journal.pone.0226546
PMCID: PMC6939901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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