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Article

Crystal structure of human LDB1 in complex with SSBP2

31 Dec 2019

Abstract excerpt

) play critical roles in cell fate decisions through partnership with multiple Lim-homeobox and Lim-only proteins in diverse developmental systems including cardiogenesis, neurogenesis, and hematopoiesis. In mammalian erythroid cells, LDB1 dimerization supports long-range connections between enhancers and genes involved in erythropoiesis, including the β-globin genes. Single-stranded DNA binding proteins (SSBPs)...

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Share to Epigenetics and DNA Methylation
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PMID: 31892537
DOI: 10.1073/pnas.1914181117

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