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Article

Effect of Cellular and ECM Aging on Human iPSC-derived Cardiomyocyte Performance, Maturity and Senescence

2020-09-29

Abstract excerpt

Cardiovascular diseases are the leading cause of death worldwide and their occurrence is highly associated with age. However, lack of knowledge in cardiac tissue aging is a major roadblock in devising novel therapies. Here, we studied the effects of cell and cardiac extracellular matrix (ECM) aging on the induced pluripotent stem cell (iPSC)-derived cardiomyocyte cell state, function, as well as response to myocar...

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Literature Corpus work
5d8bd38e-d429-5309-82ea-c163ba9ec3e1
DOI
10.1101/2020.09.28.316950
Open publication

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Effect of Cellular and ECM Aging on Human iPSC-derived Cardiomyocyte Performance, Maturity and SenescenceDOI 10.1101/2020.09.28.316950
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