Article
A Natural Model of Mouse Cardiac Myocyte Senescence.
Journal of cardiovascular translational research - 1 Dec 2016
Wang Zunzhe, Rong Xing, Luo Bihui, Qin Shanshan, Lu Lili, Zhang Xiuli, Sun Yeying, Hu Qin, Zhang Chunxiang
Abstract excerpt
Many cardiac aging studies are performed on mice first and then, due to difficulty in mouse cardiomyocyte culture, applied the rat neonatal cardiomyocytes to further determine the mechanisms in vitro. Now, the technological challenge of mouse cardiomyocyte culture has been overcome and there is an increasing need for the senescence models of mouse cardiomyocytes. In this study, we have demonstrated that the...
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