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Article

A multiple coefficient of determination-based method for parsing SNPs that correlate with mRNA expression.

Scientific reports - 27 Dec 2019

Song Fan, Tao Yu, Sun Yue, Saffen David

Abstract excerpt

In this study, we present a novel, multiple coefficient of determination (R2M)-based method for parsing SNPs located within the chromosomal neighborhood of a gene into semi-independent families, each of which corresponds to one or more functional variants that regulate transcription of the gene. Specifically, our method utilizes a matrix equation framework to calculate R2M values for SNPs within a chromosome...

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Identifiers

PMID: 31882953
DOI: 10.1038/s41598-019-56494-9
PMCID: PMC6934451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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