Article
Analysis of SNP-expression association matrices.
Proceedings. IEEE Computational Systems Bioinformatics Conference - 1 Jan 2005
Tsalenko Anya, Sharan Roded, Edvardsen Hege, Kristensen Vessela, Børresen-Dale Anne-Lise, Ben-Dor Amir, Yakhini Zohar
Abstract excerpt
High throughput expression profiling and genotyping technologies provide the means to study the genetic determinants of population variation in gene expression variation. In this paper we present a general statistical framework for the simultaneous analysis of gene expression data and SNP genotype data measured for the same cohort. The framework consists of methods to associate transcripts with SNPs affecting...
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