Article
CD38, CD157, and RAGE as Molecular Determinants for Social Behavior.
Cells - 25 Dec 2019
Higashida Haruhiro, Hashii Minako, Tanaka Yukie, Matsukawa Shigeru, Higuchi Yoshihiro, Gabata Ryosuke, Tsubomoto Makoto, Seishima Noriko, Teramachi Mitsuyo, Kamijima Taiki, Hattori Tsuyoshi, Hori Osamu, Tsuji Chiharu, Cherepanov Stanislav M, Shabalova Anna A, Gerasimenko Maria, Minami Kana, Yokoyama Shigeru, Munesue Sei-Ichi, Harashima Ai, Yamamoto Yasuhiko, Salmina Alla B, Lopatina Olga
Abstract excerpt
Recent studies provide evidence to support that cluster of differentiation 38 (CD38) and CD157 meaningfully act in the brain as neuroregulators. They primarily affect social behaviors. Social behaviors are impaired in Cd38 and Cd157 knockout mice. Single-nucleotide polymorphisms of the CD38 and CD157/BST1 genes are associated with multiple neurological and psychiatric conditions, including autism spectrum...
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