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Article

Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging.

PloS one - 1 Jan 2020

Gerasimenko Maria, Lopatina Olga, Shabalova Anna A, Cherepanov Stanislav M, Salmina Alla B, Yokoyama Shigeru, Goto Hisanori, Okamoto Hiroshi, Yamamoto Yasuhiko, Ishihara Katsuhiko, Higashida Haruhiro

Abstract excerpt

The ability of CD38 and CD157 to utilize nicotinamide adenine dinucleotide (NAD) has received much attention because the aging-induced elevation of CD38 expression plays a role in the senescence-related decline in NAD levels. Therefore, it is of interest to examine and compare the effects of age-associated changes on the general health and brain function impairment of Cd157 and Cd38 knockout (CD157 KO and CD38...

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Identifiers

PMID: 33326496
DOI: 10.1371/journal.pone.0244022
PMCID: PMC7743928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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