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Article

The protease activity of human ATG4B is regulated by reversible oxidative modification.

Autophagy - 1 Oct 2020

Zheng Xueping, Yang Zuolong, Gu Qianqian, Xia Fan, Fu Yuanyuan, Liu Peiqing, Yin Xiao-Ming, Li Min

Abstract excerpt

Macroautophagy/autophagy plays a pivotal role in cytoplasmic material recycling and metabolic turnover, in which ATG4B functions as a "scissor" for processing pro-LC3 and lipidated LC3 to drive the autophagy progress. Mounting evidence has demonstrated the tight connection between ROS and autophagy during various pathological situations. Coincidentally, several studies have shown that ATG4B is potentially...

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Identifiers

PMID: 31880198
DOI: 10.1080/15548627.2019.1709763
PMCID: PMC8386634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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