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Article

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4.

The EMBO journal - 4 Apr 2007

Scherz-Shouval Ruth, Shvets Elena, Fass Ephraim, Shorer Hagai, Gil Lidor, Elazar Zvulun

Abstract excerpt

Autophagy is a major catabolic pathway by which eukaryotic cells degrade and recycle macromolecules and organelles. This pathway is activated under environmental stress conditions, during development and in various pathological situations. In this study, we describe the role of reactive oxygen species (ROS) as signaling molecules in starvation-induced autophagy. We show that starvation stimulates formation of...

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Identifiers

PMID: 17347651
DOI: 10.1038/sj.emboj.7601623
PMCID: PMC1847657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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