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The Role of Post-Translational Modifications in Necroptosis

9 Apr 2025

Abstract excerpt

Necroptosis, a distinct form of regulated necrosis implicated in various human pathologies, is orchestrated through sophisticated signaling pathways. During this process, cells undergoing necroptosis exhibit characteristic necrotic morphology and provoke substantial inflammatory responses. Post-translational modifications (PTMs)-chemical alterations occurring after protein synthesis that critically regulate...

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PMID: 40305291
DOI: 10.3390/biom15040549

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