Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of E3, E4 Ubiquitin Ligase (UBE4B) in Human Pathologies

24 Dec 2019

Abstract excerpt

The genome is exposed daily to many deleterious factors. Ubiquitination is a mechanism that regulates several crucial cellular functions, allowing cells to react upon various stimuli in order to preserve their homeostasis. Ubiquitin ligases act as specific regulators and actively participate among others in the DNA damage response (DDR) network. UBE4B is a newly identified member of E3 ubiquitin ligases that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Histone Deacetylase Inhibitors Research
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31878315
DOI: 10.3390/cancers12010062

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of E3, E4 Ubiquitin Ligase (UBE4B) in Human PathologiesPMID 31878315Read ↗

A portrayal of E3 ubiquitin ligases and deubiquitylases in cancerSemantic proximity Read ↗

Ubiquitin becomes ubiquitous in cancerSemantic proximity Read ↗

E3 Ubiquitin Ligases as Cancer Targets and BiomarkersSemantic proximity Read ↗

E3 ligases: a ubiquitous link between DNA repair, DNA replication and human diseaseSemantic proximity Read ↗

The regulatory roles of the E3 ubiquitin ligase NEDD4 family in DNA damage responseSemantic proximity Read ↗

Genetic and Expression Aberrations of E3 Ubiquitin Ligases in Human Breast CancerSemantic proximity Read ↗

Role of ubiquitin ligases and the proteasome in oncogenesis: novel targets for anticancer therapies.Semantic proximity Read ↗

CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseasesSemantic proximity Read ↗

Functional Roles of the E3 Ubiquitin Ligase UBR5 in Cancer.Semantic proximity Read ↗

New Insights into the Role of E2s in the Pathogenesis of Diseases: Lessons Learned from UBE2O.Semantic proximity Read ↗

The Molecular Basis of Ubiquitin-Conjugating Enzymes (E2s) as a Potential Target for Cancer TherapySemantic proximity Read ↗

Role of deubiquitinating enzymes in DNA double-strand break repairSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.