Article
Computational investigation of peptide binding stabilities of HLA-B*27 and HLA-B*44 alleles.
Computational biology and chemistry - 1 Feb 2020
Bunsuz Asuman, Serçinoğlu Onur, Ozbek Pemra
Abstract excerpt
Major Histocompatibility Complex (MHC) is a cell surface glycoprotein that binds to foreign antigens and presents them to T lymphocyte cells on the surface of Antigen Presenting Cells (APCs) for appropriate immune recognition. Recently, studies focusing on peptide-based vaccine design have allowed a better understanding of peptide immunogenicity mechanisms, which is defined as the ability of a peptide to...
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