Article
In-depth phylogenetic analysis of the hemagglutinin gene of influenza A(H3N2) viruses circulating during the 2016-2017 season revealed egg-adaptive mutations of vaccine strains.
Expert review of vaccines - 1 Jan 2020
Galli Cristina, Orsi Andrea, Pariani Elena, Lai Piero Luigi, Guarona Giulia, Pellegrinelli Laura, Ebranati Erika, Icardi Giancarlo, Panatto Donatella
Abstract excerpt
Objectives: The authors conducted an in-depth phylogenetic analysis of the hemagglutinin (HA) gene of A(H3N2) identified during the 2016-2017 season to compare the circulating strains with both the egg-derived and cell-derived 2016-2017 candidate vaccine virus (CVV).Methods: 162 HA1 sequences of H3N2 viruses identified during the 2016-2017 season were phylogenetically analyzed and compared with egg-/cell-derived...
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