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Article

220 mutation in the hemagglutinin of avian influenza A (H7N9) virus alters antigenicity during vaccine strain development.

Human vaccines & immunotherapeutics - 4 Mar 2018

Liu Liqi, Lu Jian, Li Zi, Zhou Jianfang, Guo Junfeng, Li Xiyan, Liu Jia, Shu Yuelong, Wang Dayan

Abstract excerpt

Since the first confirmed case of H7N9 infection was reported in China, there have been five epidemic waves of human H7N9 infections between 2013 and 2017. The fifth wave differed from the previous four waves in that highly pathogenic avian influenza (HPAI) H7N9 viruses with multiple basic amino acids at the cleavage site were detected in humans, poultry and environmental samples. The HPAI H7N9 viruses were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29300686
DOI: 10.1080/21645515.2017.1419109
PMCID: PMC5861781

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