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Article

Design, synthesis and interaction of BRC4 analogous peptides with RAD51(241-260).

Amino acids - 1 Mar 2020

Li Jinlei, Lu Kui, Lv Mingxiu, Liu Guangbin, Ma Li, Qi Jianzhao

Abstract excerpt

Breast cancer susceptibility gene 2 (BRCA2) is an important tumor suppressor, which is participated in repair of damaged DNA by its highly conserved BRC repeat motifs regulating RAD51 protein homologous recombination and thereby preventing cell carcinogenesis. In this study, the BRCA2(1524-1548)-RAD51(241-260) complex structure was obtained based on PDB bank data 1N0W, which provided the basis for site-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Conformation, alpha-Helical

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Source

Identifiers

PMID: 31875260
DOI: 10.1007/s00726-019-02813-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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