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Article

Migraine polygenic risk score associates with efficacy of migraine-specific drugs

24 Oct 2019

Abstract excerpt

OBJECTIVE: To assess whether the polygenic risk score (PRS) for migraine is associated with acute and/or prophylactic migraine treatment response. METHODS: We interviewed 2,219 unrelated patients at the Danish Headache Center using a semistructured interview to diagnose migraine and assess acute and prophylactic drug response. All patients were genotyped. A PRS was calculated with the linkage disequilibrium pred...

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PMID: 31872049
DOI: 10.1212/nxg.0000000000000364

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