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Article

A genetic risk score is differentially associated with migraine with and without aura.

Human genetics - 1 Aug 2017

Pisanu Claudia, Preisig Martin, Castelao Enrique, Glaus Jennifer, Pistis Giorgio, Squassina Alessio, Del Zompo Maria, Merikangas Kathleen R, Waeber Gérard, Vollenweider Peter, Mwinyi Jessica, Schiöth Helgi B

Abstract excerpt

Although a number of migraine-associated single-nucleotide polymorphisms (SNP) with small effect size have been identified, little is known about the additive impact of these variants on migraine risk, frequency and severity. We investigated to what extent a genetic risk score (GRS) based on recently published, novel migraine-associated SNPs is associated with migraine prevalence, subtypes and severity in a large...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28656458
DOI: 10.1007/s00439-017-1816-5
PMCID: PMC5502071

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