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Article

Whole genome bisulfite sequencing of human spermatozoa reveals differentially methylated patterns from type 2 diabetic patients.

Journal of diabetes investigation - 1 Jul 2020

Chen Xiongfeng, Lin Qinghua, Wen Junping, Lin Wei, Liang Jixing, Huang Huibin, Li Liantao, Huang Jianxin, Chen Falin, Liu Deli, Chen Gang

Abstract excerpt

AIMS/INTRODUCTION: The incidence of type 2 diabetes mellitus is increasing worldwide, and it might partly cause metabolic disorder and type 2 diabetes mellitus susceptibility in patients' offspring through epigenetic modification. However, the underlying mechanisms remain largely unclear. Recent studies have shown a potential link between deoxyribonucleic acid methylation in paternal sperm and susceptibility to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31869513
DOI: 10.1111/jdi.13201
PMCID: PMC7378413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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