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Epigenetic profiles of pre-diabetes transitioning to type 2 diabetes and nephropathy

1 Jan 2015

Abstract excerpt

AIM: To examine DNA methylation profiles in a longitudinal comparison of pre-diabetes mellitus (Pre-DM) subjects who transitioned to type 2 diabetes mellitus (T2DM). METHODS: We performed DNA methylation study in bisulphite converted DNA from Pre-DM (n = 11) at baseline and at their transition to T2DM using Illumina Infinium HumanMethylation27 BeadChip, that enables the query of 27578 individual cytosines at CpG...

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PMID: 26265998
DOI: 10.4239/wjd.v6.i9.1113

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