Article
Identification of susceptibility locus shared by IgA nephropathy and inflammatory bowel disease in a Chinese Han population.
Journal of human genetics - 1 Mar 2020
Shi Dianchun, Zhong Zhong, Wang Meng, Cai Lu, Fu Dongying, Peng Yuan, Guo Lin, Mao Haiping, Yu Xueqing, Li Ming
Abstract excerpt
Genome-wide association studies (GWAS) had discovered several genetic risk loci for IgA nephropathy (IgAN), where the susceptibility genes of CARD9 and HORMAD2 for IgAN were also implicated in inflammatory bowel disease (IBD), suggesting a shared genetic etiology of these two diseases. The aim of this study is to explore the common susceptibility loci between IgAN and IBD and provide evidences to elucidate the...
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