Article
Measuring consistency among gene set analysis methods: A systematic study.
Journal of bioinformatics and computational biology - 1 Oct 2019
Maleki Farhad, Ovens Katie L, Hogan Daniel J, Rezaei Elham, Rosenberg Alan M, Kusalik Anthony J
Abstract excerpt
Gene set analysis is a quantitative approach for generating biological insight from gene expression datasets. The abundance of gene set analysis methods speaks to their popularity, but raises the question of the extent to which results are affected by the choice of method. Our systematic analysis of 13 popular methods using 6 different datasets, from both DNA microarray and RNA-Seq origin, shows that this choice...
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