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Article

Impact of gene annotation choice on the quantification of RNA-seq data

2021-01-08

Abstract excerpt

RNA sequencing is currently the method of choice for genome-wide profiling of gene expression. A popular approach to quantify expression levels of genes from RNA-seq data is to map reads to a reference genome and then count mapped reads to each gene. Gene annotation data, which include chromosomal coordinates of exons for tens of thousands of genes, are required for this quantification process. There are several m...

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Identifiers and source

Literature Corpus work
c012a338-e3ba-558d-953e-7eb078d425dd
DOI
10.1101/2021.01.07.425794
Open publication

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