Article

Combining multiple tools outperforms individual methods in gene set enrichment analyses

2016-03-11

Abstract excerpt

Gene set enrichment (GSE) analysis allows researchers to efficiently extract biological insight from long lists of differentially expressed genes by interrogating them at a systems level. In recent years, there has been a proliferation of GSE analysis methods and hence it has become increasingly difficult for researchers to select an optimal GSE tool based on their particular data set. Moreover, the majority of GS...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d660d80f-3118-50c5-ade4-7b6329c46252
DOI: 10.1101/042580

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Combining multiple tools outperforms individual methods in gene set enrichment analysesDOI 10.1101/042580Read

Easy and efficient ensemble gene set testing with EGSEASemantic proximity Read

Towards a gold standard for benchmarking gene set enrichment analysisSemantic proximity Read

RichPathR: a gene set enrichment analysis and visualization toolSemantic proximity Read

Differential Expression Enrichment Tool (DEET): An interactive atlas of human differential gene expressionSemantic proximity Read

Comparative study of gene set enrichment methods.Semantic proximity Read

Evaluation of Gene Set Enrichment Analysis (GSEA) tools highlights the value of single sample approaches over pairwise for robust biological discoverySemantic proximity Read

PANGEA: A New Gene Set Enrichment Tool for <i>Drosophila</i> and Common Research OrganismsSemantic proximity Read

CLEAR: Concise List Enrichment Analysis Reducing RedundancySemantic proximity Read

Benchmarking enrichment analysis methods with the disease pathway networkSemantic proximity Read

GeneSetCluster 2.0: a comprehensive toolset for summarizing and integrating gene-sets analysisSemantic proximity Read

Enhancing gene set enrichment using networksSemantic proximity Read

GSVA: gene set variation analysis for microarray and RNA-seq data.Semantic proximity Read