Article
Molecular Barcode Sequencing for Highly Sensitive Detection of Circulating Tumor DNA in Patients with Esophageal Squamous Cell Carcinoma.
Oncology - 1 Jan 2020
Hagi Takaomi, Kurokawa Yukinori, Takahashi Tsuyoshi, Saito Takuro, Yamashita Kotaro, Tanaka Koji, Makino Tomoki, Yamasaki Makoto, Nakajima Kiyokazu, Mori Masaki, Doki Yuichiro
Abstract excerpt
INTRODUCTION: Next-generation sequencing (NGS) with molecular barcodes (MB) is a novel method that enables the highly sensitive detection of circulating tumor DNA (ctDNA) in a relatively wide range of genes. OBJECTIVE: The aim of this study was to examine the utility of NGS with MB for detecting ctDNA in patients with esophageal squamous cell carcinoma (ESCC). METHODS: Five patients with ESCC who underwent...
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