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Article

Zileuton use and phenotypic features in asthma.

Pulmonary pharmacology & therapeutics - 1 Feb 2020

Thalanayar Muthukrishnan P, Nouraie M, Parikh A, Holguin F

Abstract excerpt

Zileuton, a 5-lipoxygenase (5LPO) inhibitor exerts a broad influence in the arachidonic acid (AA) pathway by blocking upstream molecules that otherwise would lead to production of an array of inflammatory leukotrienes (LT) A4-E4. Hence, it has the potential to be a drug suitable to treat complicated asthmatics. Studies have shown modest response rates for zileuton in asthmatics. OBJECTIVE: We sought to study our...

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Source

Identifiers

PMID: 31841698
DOI: 10.1016/j.pupt.2019.101872

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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